【摘要】 目的:探讨院前溶栓对肌钙蛋白T和肌红蛋白升高且ST段抬高的急性冠脉综合征(ACS)的疗效观察及临床意义。方法:选取院前肌钙蛋白T和肌红蛋白升高且ST段抬高的急性冠脉综合征患者48例,治疗组24例,予院前尿激酶静脉溶栓,对照组24例,院前不予溶栓,其他抢救措施不受限制,追踪所有患者住院期间冠脉再通情况及TIM I分级和短期内心脏事件的发生情况及预后。结果:治疗组冠脉再通情况明显优于对照组(P<0.01),短期心脏事件发生明显减少(P<0.05)。结论:院前静脉溶栓可以提高肌钙蛋白T和肌红蛋白升高且ST段抬高的ACS的血管再通率,减少短期心脏事件的发生,改善预后。更多还原

【Abstract】 Objective: To explore the therapeutic effect and clinical value of pre-hospital vein thrombolytion on acute coronary syndromes(ACS) with myoglobin and cardiac troponin T increasing and ST elevation.Method: 48 patients with ACS and both myoglobin and cardiac troponin T increasing pre-hospital were divided into therapeutic group(n=24) and control group(n=24).The therapeutic group were treated with urokinase in vein thrombolytion pre-hospital,other rescue measures were not limited in two groups.Coronary artery perforation and recent subsequent cardiac events were followed up in both groups.Result: There were far better of coronary artery perforation in therapeutic group than those in control group(P<0.01).Recent subsequent cardiac events were less in therapeutic group than in control group(P<0.05).Conclusion: Pre-hospital vein thrombolytion on ACS with myoglobin and cardiac troponin T increasing and ST elevation can improve coronary artery perforation rate,decrease recent subsequent cardiac events,and made prognosis of those patients better.更多还原