【摘要】 目的:探讨脑心综合征的临床特点和发病机制。方法:对126例既往无心脏损害的急性脑卒中患者入院后做心电图和心肌酶谱检测,同时检测102例健康体检者与之对照分析。结果:126例急性脑卒中患者心肌酶谱水平明显高于对照组,心肌酶谱异常率46.8%,心电图异常率高达69.8%,心电图的异常主要表现为心律紊乱、S-T段及T波改变、Q-T间期延长、U波出现和心梗样图型,其中脑干及丘脑基底节区病灶发生心电图及心肌酶谱异常明显高于脑叶病灶(P<0.01),出血性脑卒中发生心电图及心肌酶谱异常明显高于缺血性脑卒中(P<0.01)。结论:脑心综合征临床以心电图异常和心律失常常见,其次是心肌损伤,发生与脑卒中部位与类型等因素有关,发病机制可能与脑卒中导致植物神经功能失调、神经体液功能紊乱有关。更多还原

【Abstract】 Objective:To study clinical features and pathogenic mechanism of cerebral-cardial syndrome(CCS).Methods: Electrocardiogram(ECG) and myocardium enzyme of 126 patients with acute cerebral apoplexy were analyed with those of 102 normal control subjects.Results:The level myocardium enzyme was significant higher in 126 patients with acute cerebral apoplexy compared with that in control groups.Myocardium enzyme abnormality was 46.8%,ECG abnormality was 69.8%.Abnormal ECG major include arrhythmia,ST-T segment changes,prolonged Q-T interval,U wave appearance and myocardial infarction-like gran.Abnormal ECG and myocardium enzyme in patients with brain stem and basal ganglia lesions were more obvious than that in patients with lobar lesions(P<0.01),and in patients with hemorrhagic cerebral apoplexy higher than that in patients with ischemic cerebral apoplexy(P<0.01).Conclusion: CCS often has abnormal ECG and myocardial damage,which may be concerned with region and type of cerebral apoplexy.The mechanism of CCS may be related to neurohumoral and automatic cardiovascular dysfunction following cerebral apoplexy.更多还原