【摘要】 目的:了解糖尿病(DM)合并急性冠状动脉综合征(ACS)患者冠状动脉病变的特征。方法:冠心病监护病房收治的38例空腹血糖≥7.0mm o l/L的ACS患者(DM组),同期选择性别、年龄、吸烟、高血压、心脏肌钙蛋白和心肌梗死史相匹配的糖耐量正常的47例作为对照的ACS患者(NDM组),分别对两组进行冠状动脉造影分析及比较。结果:①DM组较NDM组血纤维蛋白原、空腹血糖、甘油三酯浓度高(P均<0.05);而高密度脂蛋白胆固醇DM组较NDM组低(P<0.05)。②DM组较NDM组冠状动脉单支病变发生率低(23.68%比44.68%,P<0.05);而多支病变的发生率高(44.73%比19.15%,P<0.05)。结论:DM并ACS患者的冠状动脉病变范围广泛,DM发生ACS是多因素协同的结果。更多还原

【Abstract】 Objective: To determine coronary artery pathological changes in diabetic patients with acute coronary syndromes(ACS).Methods: 38 patients with ACS that were admitted in hospital and blood glucose that did not have a meal ≥7.0 mmol/L(DM group),same period choice was with 47 controls matched with ACS patients for sex,age range(+2 yrs),smoke cigarette,serum cardiac troponin,hypertension and myocardial infarction history.The contrast analysis of coronary angiographic findings were carried out in these patients.Results: ① Serum fibrinogen,blood glucose and serum lipid concentration in DM group was markedly higher than that of NDM group(P<0.05).② Than NDM group,DM patients with ACS had more extensive coronary artery disease and were more likely to have triple vessel coronary artery disease(44.73% to 19.15%,P<0.05),whereas DM patients with ACS were more likely to have single coronary artery pathological changes.Conclusion: Coronary artery pathological changes is extensive in ACS diabetes patients.ACS is resulted from the conjunction of many factors.更多还原