【摘要】 目的评估地塞米松治疗重症急性胰腺炎并发急性呼吸窘迫综合症患者的有效性和安全性。方法58例重症急性胰腺炎患者按收住时间随机分成两组,治疗组除采用常规组的治疗措施外,加用大剂量地塞米松。比较两组急性呼吸窘迫综合症(ARDS)的发生率和病死率。结果58例患者中,常规治疗组有17例(占65.4%)并发ARDS,死亡10例(占38.2%);地塞米松治疗组有10例(占35.7%)并发ARDS,死亡2例(占7.1%),组间差异有统计学意义,但在腹痛缓解时间、首次排便时间、消化道出血发生率及平均住院天数上,组间差异无统计学意义。结论地塞米松对重症急性胰腺炎并发ARDS的疗效显著,能降低其病死率。更多还原

【Abstract】 Objective To evaluate the efficiency and safety of Dexamethasone(DXM) treatment in Severeacute pancreatitis(SAP) Complicated with Acute Respiratory Distress Syndrome(ARDS).Methods 58patients suffered from SAP were divided into two groups.The treatment group received traditional therayin combination with DXM. The morbidity and mortality of ARDS in the two groups were statisticallyanalyzed.Results The morbidity and mortality of ARDS in group treatment(35.7% and 7.1%) weresignificantly lower than those in group contrast(65.4% and 38.2%),there is statistical difference andthere is no statistical difference in the time of hospital stay ,abdominal pain disappeared,defecationand the rate of Digestive Hemorrhage.Conclusions The therapeutic effects of DXM on patients with SAPcomplicated with ARDS was significant, the morbidity and mortality of ARDS could be reduced.更多还原