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常规放疗与低分割放疗治疗骨转移癌疼痛的临床观察

Observation on Effect of Conventional Fraction and hypo Fraction Radiotherapy in Treating bone Metastases Patients

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【作者】 胡家柱谢方云曹小龙黎益华毛志达

【Author】 HU Jiazhu1 XIE Fangyuan2 CAO Xiaolong1 et al 1 Department of Oncology Panyu People’s Hospital Guangzhou 511400 2 Cancer Prevention and Treatment Center, Sun Yat-sen University of Medical Sciences Guangzhou 510060

【机构】 广州市番禺区人民医院肿瘤科中山大学肿瘤防治中心放疗科中山大学肿瘤防治中心放疗科 广东广州511400广东广州510060广东广州511400

【摘要】 目的观察常规放疗与低分割放疗治疗骨转移癌疼痛的临床疗效。方法90例患者分2组,常规放疗组45例:采用常规分割照射,DT200cGy/次,每周5次,DT3000~5000cGy;低分割放疗45例:采用低分割照射,300~500cGy/次,每周3~5次,DT2000~3600cGy。结果放疗起到了明显的止痛作用,常规分割放疗组与低分割放疗组止痛效果大致相似,差异无显著性(P>0.05)。结论骨转移癌的放射治疗应根据病情来决定:对一般情况好,预计生存期长的患者应积极给予全剂量的分割治疗,而对于病情相对较重、行动不方便、预计生存期短的患者,应采取低分割照射,同样可以起到止痛作用。

【Abstract】 Objective To observation the pain relief efficacy with conventional fraction and hypo fraction radiotherapy for bone metastases.Methods Of 90 patients with bone metastases , 45 cases received conven- tional fraction : DT200cGy/f,5 fractions per week DT3000~5000cGy.45 cases received hypo fraction : DT300~ 500cGy/f,3~5 fraction per week, DT2000-3600cGys.Results Radiotherapy can produce a higher pain relief rate of bone metastases . Compared conventional fraction with hypo fraction, no significant difference was found (P>0.05).Conclusion Radiotherapy of bone metastases should be determined by the patient condition. For the patients with long life span should be treated actively by conventional fraction and high doses . The patients with severe disability and pain should be treated with hypo fraction.

【关键词】 骨转移癌放射治疗疼痛
【Key words】 Bone metastases Radiotherapy Pain
  • 【文献出处】 国际医药卫生导报 ,International Medicine & Health Guidance News , 编辑部邮箱 ,2006年10期
  • 【分类号】R738.1
  • 【被引频次】2
  • 【下载频次】37
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