【摘要】 目的探讨输血传播病毒(transfusiontransmittedvirus,TTV)的实验室诊断及临床特点。方法用半巢式聚合酶链反应方法检测72例非甲—庚型肝炎患者血清中TTV-DNA。结果72例非甲—庚型肝炎患者血清中,有18例检出TTV-DNA。TTV感染者病情有轻有重,表现为急性无黄疸性肝炎、急性黄疸性肝炎及轻度慢性肝炎。结论非甲—庚型肝炎患者血清中存在TTV的感染,并可能是致病原因。临床表现为急性或轻度慢性肝炎,组织学上可见肝细胞变性、坏死和肝组织淋巴细胞浸润、纤维增生、汇管区炎症。TTV除血传播外,可能存在其它的传播方式。更多还原

【Abstract】 Objective To study laboratory diagnosis of transfusion transmitted virus(TTV) and it’s clinicalcharacter.Methods TTV-DNA in serum of 72 patients with hepatitis Non-A to G were detected by Hn-PCR.Results18/72 of patients with hepatitis Non-A to G were detected TTV-DNA.The symptom of patients infected with TTV couldbe gently or severely,and it’s clinical manifestations were acute non-icteric hepatitis、acute icteric hepatitisor mild chronic hepatitis.Conclusions Patients with hepatitis Non-A to G were infected with TTV probably,andTTV could be one of reasons to cause the disease.The clinical manifestations of patients infected with TTV wereacute or mild chronic hepatitis, and liver cell degeneration、necrosis or liver tissue infiltrated withLymphocyte、Fibrosum proliferation、inflammation could be seen on histology.There were some other ways of TTVtransmission except blood.更多还原