【摘要】 [目的]探讨早期梅毒的临床特征、诊断及治疗原则。[方法]对哈尔滨口岸地区1999～2005年资料完整的125例早期梅毒病例进行回顾性分析。[结果]流行特点为：梅毒患者以50岁以内性活跃人群为主；以服务行业、无业人员为多；传染途径以非婚性接触感染居多。无症状潜伏梅毒21例,占梅毒患者总数的16．80％,其主动就诊者较少,多为产前、术前、健康检查或性伴患梅毒时追查出来；一期梅毒硬下疳多为单发(70．96％),多发生在外生殖器上(87．09％),但生殖器以外部位也有发生；二期梅毒皮疹中扁平湿疣有明显增多趋势；一、二期梅毒同时存在占6．40％,应值得注意；苄星青霉素仍然是治疗梅毒首选药物,没有发现耐青霉素的梅毒螺旋体。[结论]梅毒是一种对人体危害较大的性传播疾病,其临床表现及血清学改变复杂多变,必须准确掌握梅毒流行病及临床特点,及时发现病人,提高早期梅毒的诊断率,做到尽早发现,规范治疗,减少梅毒的传播。更多还原

【Abstract】 Objective To investigate the clinical characteristics,diagnosis and treatment d the earlier syphilis cases.Method A completed clinical informaiton of 125 earlier syphilis cases from 1999 to 2005 at Harbin seaport was collected and a retrospective study was conducted.Result The epidemic characteristics were:The majority of the positives were under 30 years old with active sexual behaviors,and many of them were waiters or unemployed;the main infection routes were sexual intercouse:the number of latent syphilis cases with no symptom was 21 examples (16.80%).They seldom went to hospital to have examination,mostly found in the prenatal period,preoperation,health inspection or after the sex partner got the syphilis.The hard chancre of primary syphilis was single lesion mostly (70.96%),and most on genital skin (87.09%),oth- er parts also had (12.91%).The fiat condyloma among secondary syphilid had the increase tendency obviously;primary and secondary syphilis were present at 6.4%,this should be worthy of remark.The primary medicine for syphilis treatment still was Penicillin G Benzathine,and peni- cillin-resistant treponema pallidum was not found.Conclusion The syphilis is a sexually transmitted disease of being harmful to human body, its clinical performance and serum changing were complex and variable,so we should accurately master clinical characteristics of syphilis,identify patient as early as possible,increase the diagnosis rate of earlier syphilis,and take standant treatment to reduce the spreading of syphilis.更多还原