【摘要】 利用羧甲基壳聚糖(CM CS)与甘油磷酸盐(GP)互配,制备了在25℃~70℃具有响应功能的透明水凝胶体系。探讨了CM CS羧甲基取代度(D S)、GP的浓度和盐酸的浓度等因素对凝胶性能和透明度的影响。结果表明,D S介于0.3~0.6的CM CS与GP互配,可以得到温敏性透明状水凝胶,其透明度随着D S的增大而递增;随环境温度的升高和恒温时间的延长,其透明度降低;随着D S的增大,环境温度和恒温时间对配合物凝胶透明度的影响减弱。更多还原

【Abstract】 In this paper,thermo-sensitive gelling systems based on a carboxymethyl chitosan/glycerophosphate salt(CMCS/GP) complex were prepared.These systems can be held liquid below room temperature and they form transparent gels when heated.Various factors that affected the properties of gels were tested,including the degree of substitution(DS) of CMCS,the concentration of GP and HCl,etc.The effects of various factors on the transparency of the complex gels were also tested in the paper.The results show that the thermo-sensitive transparent hydrogels can be prepared by using CMCS with DS between(0.3) and(0.6),and the transparency of the hydrogels increases with an increase in the DS of CMCS.With increasing the environmental temperature or prolonging the thermostatic time,the transparency of the hydrogels decreases.With an increase in the DS of CMCS,the effect of the environmental temperature or the thermostatic time on the transparency of the hydrogels reduces.更多还原