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康艾注射液联合化疗治疗中晚期非小细胞肺癌的临床研究

Kangai injection mixed with chemotherapy in intermediate and advanced-stage non-small cell lung cancer

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【作者】 温继育谢忠谢杰荣冯丽萍

【Author】 WEN Ji-yu,XIE Zhong,XIE Jie-rong,FENG Li-ping(Department of Oncology,Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001,China)

【机构】 广东医学院附属医院肿瘤内科广东医学院附属医院肿瘤内科 广东湛江524001广东湛江524001

【摘要】 目的:观察康艾注射液在中晚期非小细胞肺癌综合治疗中的作用。方法:将78例中晚期非小细胞肺癌患者随机分为治疗组(n=40)和对照组(n=38)。治疗组用康艾注射液加化疗,并与单纯化疗组进行对照。两组化疗方案相同。结果:治疗组近期有效率为72.5%,而对照组为47.4%,两组比较差异有显著性(P<0.05);治疗组和对照组患者的生活质量karnofsky评分的好转率分别为87.5%和55.3%,两组比较差异有显著性(P<0.01);对照组和治疗组患者治疗后血象均降低,但以对照组更为明显,差异有显著性(P<0.01);结论:康艾注射液可以明显提高中晚期非小细胞肺癌患者的近期疗效和生活质量,减少血象降低的几率。

【Abstract】 Objective: To observe the effect of Kangai injection on patients with intermediate and advanced-stage non-small cell lung cancer(NSCLC).Methods: Seventy-eight patients with stage ⅢB/IV NSCLC were randomly divided into two groups: treatment group(n=40) received Kangai injection and chemotherapy,and control group(n=38) only accepted chemotherapy.Results: The short-term effect,Karnofsky scores of life quality,and the incidence of pancytopenia in treatment group were superior to those in control group((72.5%) vs 47.4%,P<0.05; 87.5% vs 55.3%,P<0.01;P<0.01).Conclusion: Kangai injection can improve the short-term effect,quality of life,and pancytopenia prevalence in patients with intermediate and advanced-stage NSCLC.

【关键词】 肺癌化疗生活质量康艾注射液
【Key words】 lung cancerchemotherapyquality of lifeKangai injection
  • 【文献出处】 广东医学院学报 ,Journal of Guangdong Medical College , 编辑部邮箱 ,2006年01期
  • 【分类号】R734.2
  • 【被引频次】6
  • 【下载频次】126
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