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电泳芯片上低工作电压分离模式的电场模拟分析

Electric field simulation of separation mode on low voltage electrophoresis chip

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【作者】 温志渝徐溢李霞吕君江朱维维

【Author】 WEN Zhi-yu1,XU Yi1,2,LI Xia1,Lü Jun-jiang2,ZHU Wei-wei1 ( 1. Microsystem Research Center, Optic and Electric Engineering College, Chongqing University; Chongqing 400044, China; 2. Chemistry and Chemical Engineering College, Chongqing University, Chongqing 400044, China )

【机构】 重庆大学光电学院微系统研究中心重庆大学化学化工学院重庆大学光电学院微系统研究中心 重庆400044重庆400044重庆大学化学化工学院重庆400044

【摘要】 本文根据电泳芯片的低工作电压分离理论模型,选定采用对分离管道侧壁阵列电极以等间距施加电压的方式作为电场模拟分析的模型。利用ANSYS有限元软件分析系统,对微分离管道中的电场分布进行模拟仿真分析。重点探讨了阵列电极的布置方式、电极个数和位置、微分离管道形状、电极表面绝缘层等因素对微管道中电场分布的影响;详细计算和优化了利用电极阵列实现低工作电压分离过程中,分离微管道及电极阵列的基本设计和结构参数。这为研制一种微型化的低电压电泳芯片系统奠定了一定的理论基础。

【Abstract】 According to the theory model of low voltage electrophoresis on CE chip, arrayed electrodes was applied to realize the moving Electric Field (EF) on silicon CE chip. Analytical model was established in which arrayed electrodes were deposited on the two sides of separating channel, and working low voltage was applied in the mode of equal distance. By means of ANSYS definite element software, effects of separating channel system and arrayed electrodes on electric fields in the low voltage CE chip were simulated by computer. The factors, such as: position of arrayed electrodes, number of arrayed electrodes, shape of micro channel, insulator on arrayed electrodes, etc., were studied and optimized in detail. The basic structure design of the low voltage CE chip was obtained by the simulated results. The work is of great potential importance for low voltage CE chip design and research.

【基金】 国家自然科学基金资助项目(90307015,20007005);重庆市自然科学基金重点项目(8985-2005,2006BA4012)
  • 【文献出处】 光电工程 ,Opto-Electronic Engineering , 编辑部邮箱 ,2006年09期
  • 【分类号】TN492
  • 【被引频次】4
  • 【下载频次】148
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