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脾虚大鼠脑神经生化指标变化的实验研究
Experimental Study on the Changes of Biochemical Indicators of Cerebral Nerves in Spleen Deficiency Rats
【摘要】 研究中医脾虚证对大鼠脑记忆功能生化指标的影响。用泻下和劳倦法制作脾虚大鼠模型,再用四君子汤治疗,检测大鼠的脑生化指标。结果:脾虚组AchE明显升高,与正常组比较差异非常显著(P<0.01),与四君子汤治疗组比较,差异显著(P<0.05);脾虚组NO含量、NOS活性明显较正常组及四君子汤治疗组低(P<0.05)。结论:脾虚影响大鼠脑记忆功能的生化指标。
【Abstract】 To investigate the influence of spleen deficiency on memory.The model rats of spleen deficiency were made by diarrhea and fatigue,and then were administered sijunzi decoction,the levels of AchE,NOS,NO in the brain tissue were tested.The result showed that the levels of AchE in spleen deficiency group were obviously higher than that of control group and sijunzi decoction group(P<0.01,P<0.05),and NOS,NO was significantly lower than that of another two groups(P<0.05).Conclusions: Spleen deficiency depresses rats’ ability of learning and memory.
【Key words】 spleen deficiency; sijunzi decoction; acetylcholinesterase; nitric oxide synthetase; nitric oxide; rat;
- 【文献出处】 福建中医学院学报 ,Journal of Fujian College of Traditional Chinese Medicine , 编辑部邮箱 ,2006年02期
- 【分类号】R256.3
- 【被引频次】36
- 【下载频次】199