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槲皮素分子印迹聚合物的制备及固相萃取性能研究

Preparation of quercetin-imprinted polymer and its property as a sorbent for solid phase extraction

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【作者】 颜流水井晶黄智敏温振东刘凤涛

【Author】 YAN Liu-shui~*,JING Jing,HUANG Zhi-min,WEN Zhen-dong and LIU Feng-tao(Department of Environment and Chemical Engineering,Nanchang Institute of Aeronautical Technology,Nanchang 330034)

【机构】 南昌航空工业学院环境与化学工程系南昌航空工业学院环境与化学工程系 南昌330034南昌330034

【摘要】 采用分子印迹技术,以槲皮素为模板分子,丙烯酰胺为功能单体,乙二醇二甲基丙烯酸脂为交联剂,通过热引发聚合,制备了槲皮素分子印迹聚合物,并通过装入固相萃取柱试验了聚合物对槲皮素的选择性能。结果表明,该分子印迹聚合物对槲皮素具有高度选择性,为从天然产物中高效分离富集黄酮活性成分槲皮素提供了一种新材料。

【Abstract】 A quercetin-imprinted polymer was synthesized successfully under the condition of heat-initiation through a molecular imprinting technology by using quercetin as the template molecule,acrylamide as the functional monomer and ethylene glycol dimethacrylate as the cross linking monomer,and the selectivity of the polymer for substrate was investigated by solid-phase extration column packed with the molecular imprinted polymer.The results revealed that the polymer exhibited high affinity for quercetin and good selectivity among the tested compounds.It′s likely to be a novel material for selective enrichment and determination of trace quercetin in traditional Chinese medicines.

【基金】 江西省自然科学基金项目(0520069);江西省教育厅科技计划项目(赣教技字[2005]166号)
  • 【文献出处】 分析试验室 ,Chinese Journal of Analysis Laboratory , 编辑部邮箱 ,2006年05期
  • 【分类号】O631.3;O658.2
  • 【被引频次】86
  • 【下载频次】1435
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