【摘要】 研究了丹参酮ⅡA(TS)在碳糊电极(CPE)上的伏安行为,结果表明:在0.2 mol/L BR(pH 2.4)的乙醇/水(40∶60,V/V)中,TS的羰基发生单电子、单质子的氧化还原反应,该反应是一个有吸附特征的可逆过程;还原产物半醌自由基能稳定存在,这可能是由于CPE中疏水有机相阻止了该自由基的岐化反应。还原峰和氧化峰的峰电位分别为-0.31和-0.24 V(vs,SCE),二阶导数氧化峰峰电流与TS浓度在1.2×10-8~8.2×10-7mol/L范围内呈线性关系;检出限为4.1×10-9mol/L。本方法可用于复方丹参片中丹参酮总含量的测定。更多还原

【Abstract】 The voltammetric behavior of tanshinone ⅡA（TS） on carbon paste electrode（CPE） was studied.In 0.2 mol/L BR buffer（pH 2.4）-ethanol/water（40∶60,V/V） medium,the carbonyl group of TS under went a one-electron and one-proton redox reaction at CPE,which was a reversible process with adsorption character.The semiquinone radical of TS as reduction product existed stably on CPE,which might be that hydrophobic organic phase inhibited the disproportionation reaction of the radical of TS. The peak potentials of the reduction and oxidation were-0.31 V and-0.24 V（vs.SCE）,respectively.The second-order derivative oxidation peak current showed a linear relationship with the concentration of TS in the range of 1.2×10^-88.2×10^-7 mol/L,and the detection limit was 4.1 × 10^-9 mol/L.The voltammetric method proposed can be used to determine the total tanshinone in compound Danshen tablet.更多还原