【摘要】 以Eu(hfc)3和Pr(hfc)3为手性镧系位移试剂(CLSR),比较了两种CLSR对2,4-滴丙酸甲酯的1HNMR和13C NMR谱手性分离效果,结果表明:Pr(hfc)3比Eu(hfc)3对手性中心相连的甲基具有更好的手性分离效果。首次应用Pr(hfc)3测定了盖草能、稳杀得和喹禾灵3种手性芳氧丙酸酯类除草剂的1HNMR和13CNMR谱,其1HNMR谱分离度R约为1,盖草能和喹禾灵的13C NMR谱分离度R大于1.5,说明1H NMR和13CNMR谱手性分离效果适用于对映体纯度测定。与手性色谱法相比,CLSR-NMR法测定对映体纯度具有操作简便、分析速度快的显著优势。更多还原

【Abstract】 The chemical shift non-equivalence in ¹H and 13 C nuclear magnetic resonance （NMR） of dichlorprop-methyl were compared by using Eu-heptafluorohydroxy-methylene-d-camphorato （hfc）₃ and Pr（hfc）₃ as chiral lanthanide shift reagents （CLSR）, it showed that Pr（hfc）₃ was more effective than Eu（hfc）₃. Pr（hfc）₃ was used as firstly in detecting the chemical shift non-equivalence of ¹H and 13 C NMR of three arylphenoxypropionate herbicides, quizalofop-ethyl, halxoyfop-etotyl and fluazifop-butyl. The result showed that the chiral resolutions of ¹H NMR of three herbicides were about 1, and the chiral resolutions of 13 C NMR of quizalofop-ethyl and halxoyfop-etotyl were more than 1.5. That means the chiral resolutions of ¹H NMR and 13 C NMR are fit for determining the enantiomeric purity. CLSR-NMR method is simpler and faster than chiral chromatographic method in the determination of the enantiomeric purity.更多还原