【摘要】 目的:探讨腹腔镜卵巢打孔术治疗难治性多囊卵巢综合征(PCOS)合并不孕的临床价值、适应证及机理。方法:对符合PCOS标准的不孕症47例采用腹腔镜电针双侧卵巢打孔术,观测术后排卵、妊娠、流产情况,比较手术前后血FSH,LH和T值的变化及月经情况的改变。结果:术后血清雄激素(T)及黄体生成激素(LH)明显下降,术后排卵率为85.1%。妊娠率为61.7%,早期流产率为10.3%,无1例发生卵巢过度刺激综合征(OHSS)。结论:腹腔镜卵巢打孔术可提高PCOS合并不孕患者的自然排卵率及对克罗米芬的敏感性,从而提高妊娠率,是PCOS不孕症特别是难治性PCOS患者恢复卵巢生理功能的有效手段,但应掌握手术时机和手术指征。术后3个月未妊娠者尽早采用促排卵药物以提高妊娠率。更多还原

【Abstract】 Objective:To evaluate the clinical applying value,inclication and mechanism of insulated needle cautery laparoscopy for treatment of polycystic ovarian syndrome(PCOS)in clomiphene-resistant anovulatroy women.Methods:Forty-seven patients were clomiphene-resistant anovulatory with PCOS.Laparoscopic ovarian drilling use an insulated needle cautery.They were observed the changes of blood FSH,LH,T and the ovuatory rate,pregnancy rate,abortion rate.Results:The ovalation rate was 85.1%,the pregnancy rate was 61.7%,the abortion rate was 10.3%,the level of blood LH and T decreased apparently.Conclusions:Laparoscopic ovarian drilling is an effective alternative treament in clomiphene-resistant anovulatroy women with PCOS.The use of an insulated needle cautery is rapid effective,simple,safe,minimal invation and less adhesion.更多还原