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深黄被孢霉及其脂溶性组分对高脂饮食小鼠的影响
Effects of Mortierella isabellina and Lipid Extraction on Mice with High-fat Diet
【摘要】 研究深黄被孢霉菌粉及其脂溶性组分对脂代谢紊乱小鼠的调节作用.小鼠膳食高脂饲料13周后建模成功,随后以菌粉及其提取物继续喂食7周.实验结果证明菌粉治疗作用的靶位点之一是白色脂肪组织,可引起小鼠体质量显著性下降;菌粉及其提取物能降低高脂饮食小鼠的TC/HDL-c的水平,改善血浆胆固醇比例.
【Abstract】 Concerns on the effects of Mortierella isabellina and unsaturated fatty acids extracted on hyperlipidemic mice.Mice were fed with high-fat diet for 13 weeks,then with the fungi-derived unsaturated fatty acids for 7 weeks.The result suggested that the white adipose tissue may be one of the main therapeutic targets,resulting in the reduction of body weight;and decrease TC/HDL-c level in high-fat diet mice,ameliorate the ratio of cholesterol in plasma as well by Mortierella isabellina.
【关键词】 高脂饮食;
深黄被孢霉;
多不饱和脂肪酸;
【Key words】 high-fat diet; Mortierella isabellina; polynsaturated fatty acids;
【Key words】 high-fat diet; Mortierella isabellina; polynsaturated fatty acids;
【基金】 福建省自然科学基金资助项目(C0440001)
- 【文献出处】 福建师范大学学报(自然科学版) ,Journal of Fujian Normal University(Natural Science Edition) , 编辑部邮箱 ,2006年02期
- 【分类号】R285.5
- 【下载频次】29