【摘要】 [目的]探讨充血性心力衰竭(congestion heart failure,CHF)与免疫功能变化情况。[方法]测定了53例 CHF患儿及50例健康儿童T淋巴细胞亚群、T淋巴细胞转化率、免疫球蛋白及补体(C3)作分析比较。[结果]CHF组 CD3、CD4、CD8、CD4／CD8、T淋巴细胞转化率均显著降低,而IgG、C3升高。[结论]CHF影响患儿免疫功能,并可激活补体系统,造成免疫损伤,加重心功能不全。更多还原

【Abstract】 [Objective] To learn the change of immune ability under congestion heart failure(CHF). [Method] 53 CHF and 50 generally healthy children were analyzed and compared on T-lymphocyte subgroup, T-lymphocyte alteration rate,immunoglobulin and complement(C3).[Result] The concentration of CD3、XD4、CD8、CD4/CD8 andT-lymphocyte alteration rate of CHF children were obviously decreased, while IgG and C3 increased. [Conclusion] CHF could weaken the immune ability of children and activate the complement system, thus worsen the heart failure by immune damage.更多还原