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小儿充血性心力衰竭与免疫功能变化

Change of immune ability of congestion heart failure children

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【作者】 阮兢邓向红蔡仕俊黄良锦林茹珠何洁冰

【Author】 RUAN Jing,DENG Xiang-hong,CAI Shi-jun;HUANG Liang-jin, LIN Ru-zhu,HE Jie-bing.(Department of Pediatric,Laboratory Center,Zhongshan City People’s Hospital ,Zhangshang, Guangdong 528403,China)

【机构】 中山市人民医院儿科中山市人民医院检验中心 广东中山528403广东中山528403

【摘要】 [目的]探讨充血性心力衰竭(congestion heart failure,CHF)与免疫功能变化情况。[方法]测定了53例 CHF患儿及50例健康儿童T淋巴细胞亚群、T淋巴细胞转化率、免疫球蛋白及补体(C3)作分析比较。[结果]CHF组 CD3、CD4、CD8、CD4/CD8、T淋巴细胞转化率均显著降低,而IgG、C3升高。[结论]CHF影响患儿免疫功能,并可激活补体系统,造成免疫损伤,加重心功能不全。

【Abstract】 [Objective] To learn the change of immune ability under congestion heart failure(CHF). [Method] 53 CHF and 50 generally healthy children were analyzed and compared on T-lymphocyte subgroup, T-lymphocyte alteration rate,immunoglobulin and complement(C3).[Result] The concentration of CD3、XD4、CD8、CD4/CD8 andT-lymphocyte alteration rate of CHF children were obviously decreased, while IgG and C3 increased. [Conclusion] CHF could weaken the immune ability of children and activate the complement system, thus worsen the heart failure by immune damage.

  • 【文献出处】 中国儿童保健杂志 ,Chinese Journal of Child Health Care , 编辑部邮箱 ,2006年03期
  • 【分类号】R725.4
  • 【被引频次】4
  • 【下载频次】41
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