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健脾加味清毒方对儿童铅中毒的驱铅研究

Clinical study of effects of traditional Chinese medicine on discharging Pb poisoning in children

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【作者】 谭美珍林岚张春玲陈力彭静宜曾超宜陈咏冲

【Author】 TAN Mei-zhen,LIN Lan, ZHANG Chun-ling,CHEN Li, PENG Jing-yi,ZENG Chao-yi,CHEN Yong-chong.(Department of Pediatrics, Guangzhou Children’s Hospitol, Guangzhou, Guangdong 510120,China;The First Affiliated, Hospital Zhongshan Medical University,Guangzhou,Quangdong 510080,China)

【机构】 广州市儿童医院儿内科中山医科大学附属第一医院 广东广州510120广东广州510120广东广州510080

【摘要】 [目的]探讨中药驱铅对儿童血Pb及血Zn、Cu、Fe、Ca、Mn水平的影响。[方法]184例血铅≥0. 483μmol/L(100 μg/L)的患儿随机分为治疗组和对照组,治疗组服用健脾加味清毒方,对照组采用安慰治疗,观察30 d,检测驱铅前后两组患儿血Pb及血Zn、Cu、Fe、Ca、Mn水平。[结果]治疗组患儿服药后的血Pb明显低于服药前,血Zn 水平明显高于服药前,差异有显著性(P<0.01,0.05);与对照组比较,血Pb明显降低(P<0.01),血微量元素Fe、Cu、Ca、 Mn水平无明显差异(P>0.05)。[结论]中药对儿童早期铅中毒的驱铅效果好,不存在微量元素失衡。

【Abstract】 [Objective] To observe the effect of the content of Pb、Zn、Cu、Fe、Ca and Mn after the treatment by traditional Chinese medicine. [Methods] 184 children with blood lead level exceeding 0.1μg/ml were randomly divided into the treatment group and control group. The treatment group with traditional Chinese medicine, the control group with no drug, the observation period for both 30 days. [Results] The blood lead in treatment group was significantly lower than that of the children cured by traditional Chinese medicine(P<0. 001) ,the blood Zn increased(P<0. 05); The blood lead in treatment group was significantly lower than in the control group(P<0. 001) , while the content of Cu、Fe、Ca、Mn remained stable(P>0. 05). [Conclusion] Traditional Chinese medicine was effective in curing children with Pb poisoning, which would not cause trace elements inbalance.

【关键词】 铅中毒中药微量元素儿童
【Key words】 Pb poisoningtraditional Chinese medicinetrace elementschildren
  • 【文献出处】 中国儿童保健杂志 ,Chinese Journal of Child Health Care , 编辑部邮箱 ,2006年03期
  • 【分类号】R272
  • 【被引频次】11
  • 【下载频次】459
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