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氨溴索辅助治疗新生儿胎粪吸入综合征
Efficacy of ambroxol in the treatment of meconium aspiration syndrome
【摘要】 目的:探讨氨溴索辅助治疗新生儿胎粪吸入综合征的效果。方法:将46例胎粪吸入综合征患儿随机分为治疗组(26例)和对照组(20例),两组均采用呼吸机辅助通气及常规治疗,治疗组在上述治疗的基础上加用氨溴索静脉滴注。结果:治疗组8 d后X线胸片好转率及治疗后72 h、84 h、96 h的平均气道压(MAP)和氧合指数(PaO2/FiO2)等指标分别与对照组相比,差异均有统计学意义(P<0.05)。结论:氨溴索辅助治疗新生儿胎粪吸入综合征效果满意,未见明显不良反应。
【Abstract】 Objective:To investigate the therapeutic efficacy of ambroxol in the treatment of meconium aspiration syndrome.Methods: 46 cases of meconium aspiration syndrome newborns were divided into the treatment group(26 cases) and the control group(20 cases).Results: The improvement rates of chest X-ray after 8 days,mean airway pressure(MAP) and PaO2/FiO2,after 72 h,84 h and 96 h in two groups were significantly different(P<0.05).Conclusions: The ambroxol could control the attack of meconium aspiration syndrome without side effect.
- 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2006年06期
- 【分类号】R722.1
- 【被引频次】5
- 【下载频次】39