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咪达唑仑治疗难治性惊厥持续状态29例

Midazolam treats the twenty-nine childrens with refractory generalized convulsive status epilepticus

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【作者】 石俊英

【Author】 SHI jun-ying(The Third Hospital of Anyang,Henan Anyang 455000,China)

【机构】 河南省安阳市第三人民医院 河南安阳455000

【摘要】 目的:研究咪达唑仑治疗难治性惊厥持续状态的疗效及临床价值。方法:对29例难治性惊厥持续状态患儿首先给予咪达唑仑负荷量0.2mg/(kg.次),30min后给予维持量1.0μg/(kg.min),每30min增加维持剂量1.0μg/(kg.min)直到惊厥停止。结果:29例患儿中26例在咪达唑仑维持量8.0μg/(kg.min)内惊厥停止,未发现明显不良反应。结论:咪达唑仑是治疗难治性惊厥持续状态的安全、有效的药物。

【Abstract】 Objective: To study the efficacy and clinical value of midazolam in treating refractory generalized convulsive status epilepticus.Methods: The twenty-nine children of refractory generalized convulsive status epilepticus were,first,given a charge of midazolam of 0.2 mg/kg.After half an hour,a maintenance dose of 1.0 μg/(kg·min) was added,and then a dose of 1.0 μg/(kg·min) was added every 30 minutes until the convulsion stopped.Results: Conversion stopped in 26 cases when less than maintenance doses of 8.0 μg/(kg·min) of midazolam were used and no side effect was found.Conclusions: Midazolam is a safe and effective medicine in treating refractory generalized convulsive status epilepticus.

  • 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2006年02期
  • 【分类号】R720.597
  • 【被引频次】7
  • 【下载频次】91
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