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甲硝唑联合云南白药灌肠治疗小儿慢性结肠炎临床观察

Clinical observation of metronidazole and Yunnan Baiyao in the treatment of chronic colitis in children by enteroclysis

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【作者】 陈昌斌游洁玉陈志勇罗艳红赵红梅

【Author】 CHEN Chang-bin, YOU Jie-yu, CHEN Zhi-yong, et al (The Children’s Hospital of Hunan Province, Hunan Changsha 410007, China)

【机构】 湖南省儿童医院湖南省儿童医院 湖南长沙410007湖南长沙410007

【摘要】 目的:探讨甲硝唑联合云南白药灌肠治疗小儿慢性结肠炎的疗效。方法:将100例小儿慢性结肠炎患儿随机分为两组,在给予常规治疗的基础上,治疗组加用甲硝唑和云南白药保留灌肠,对照组加用黄连素保留灌肠,治疗14d后观察两组疗效。结果:治疗组、对照组总有效率分别为94.0%、46.0%,差异有统计学意义(χ2=27.43,P<0.01)。组间比较显示:治疗组的近期治愈率明显高于对照组(χ2=12,P<0.01)。结论:甲硝唑联合云南白药灌肠治疗小儿慢性结肠炎疗效显著,值得临床推广。

【Abstract】 Objective: To explore the effect of metronidazole and Yunnan Baiyao in the treatment of children with chronic colitis by enteroclysis. Methods: 100 children with chronic colitis were randomly divided into two groups,50 cases in control group and 50 cases in treatment group. In addition to the normal treatment, enteroclysis was used with metronidazole and Yunnan Baiyao in the treatment group, while enteroclysis was used with berberine in the control group. Results: The total effective rates of treatment group and control group in the first 14 days of treatment were 94.0% and 46.0%, respectively. There was significant difference between these two groups ( χ2 = 27.4, P < 0.01), the cure rate of short term treatment group was significantly higher than that of control group( χ2 = 12, P < 0.01). Conclusions: Metronidazole and Yunnan Baiyao in treating children with chronic colitis is effective by enteroclysis.

【关键词】 小儿甲硝唑云南白药灌肠慢性结肠炎
【Key words】 ChildrenMetronidazoleYunnan baiyaoEnteroclysisChronic colitis
  • 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2006年01期
  • 【分类号】R725.7
  • 【下载频次】74
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