【摘要】 目的研究4年来我院胆道感染的细菌分布、变迁及其中大肠埃希菌ESBLs(超广谱β-内酰胺酶)阳性率的情况。方法取2001年1月~2004年12月在我院确诊为胆道感染行内镜鼻胆管引流或外科手术采集的胆汁标本进行培养、菌种鉴定及药敏分析。结果2001~2004年大肠埃希菌在胆道感染的细菌中所占比率分别为9.3%、19.8%、25.0%、32.3%;其中ESBLs(超广谱β-内酰胺酶)阳性大肠埃希菌的比率分别为44.4%、52.2%、73.1%、85.2%。结论胆道感染的细菌中主要以阴沟肠杆菌、大肠埃希菌、肺炎克雷伯菌、粪肠球菌、铜绿假单胞菌等为主,其中阴沟肠杆菌、肺炎克雷伯菌近年来有所减少,大肠埃希菌近年来明显增多,且大肠埃希菌中ESBLs阳性率逐年上升。更多还原

【Abstract】 Objective To investigate the changes of bacteria inducing biliary tract infections and positive ratio of ESBLs in E.coli in our hospital in recent 4 years.Methods All bile specimen were collected from surely patients with biliary infection by TBNB dripping or surgery,from Jan 2001 to Dec 2004.All specimen were cultured,and followed by bacterial distinguish and antibiotics resistance assay.Results E.coli accounted for 9.3%,19.8%,25.0% and 32.3% in all pathogens from 2001 to 2004,respectively.The E.coli which produced ESBLs accounted for 44.4%,52.2%,73.1% and 85.2% in all E.coli from 2001 to 2004 respetively.Conclusion E.cloacae,E.coli,K.pneumoniae,E.faecalis and P.aeruginosa are the most important pathogens of biliary tract infections.The ratio of E.cloacae and K.pneumoniae in all bacteria is decreasing,in contrary to the increasing ratio of E.coli in recent years.The E.coli which produces ESBLs is increasing year by year.更多还原