【摘要】 猪戊型肝炎是一种新发现的传染病,其病原戊型肝炎病毒(HEV)是一种无囊膜的RNA病毒,基因组全长为7.2 kb~7.4 kb。研究发现,世界上许多国家的猪群中普遍存在较高的HEV抗体,也检测到猪戊型肝炎病毒,与猪接触的职业人群的血清抗HEV抗体均高于非职业人群,有些国家从猪群中分离到的HEV核苷酸序列与当地居民感染的HEV具有高度的同源性。据此认为猪戊型肝炎是一种人兽共患病,猪可能作为戊型肝炎的贮存宿主,在人类病毒性肝炎流行病学中具有重要的地位,对于公共卫生、异种器官移植和食品安全等构成潜在威胁。更多还原

【Abstract】 Swine hepatitis E is a newly identified disease that is caused by hepatitis E virus(HEV).HEV is a single-strand RNA virus without an envelope.The genome of HEV is approximate 7.2 kb to 7.4 kb.The presence of HEV RNA and antibodies in pigs has been demonstrated in many countries.Higher anti-HEV titer was observed in people who contacted with pigs.Also in some coutries,the HEV strain isolated from the pigs was found to share a highly identify with that from humans in the same region.It has been conseuqently hypothesized that swine hepatis E is a potentically zoonotic agent and swine might act as an animal reservoir in the epidemiology of HE in humans,thus putting public health,xenogenic organ transplantation and food safety at a certain risk.更多还原