【摘要】 β-防御素是近年来发现的一类广泛存在于动物体内具有广谱抗微生物活性的阳离子多肽。它具有抗细菌、真菌、螺旋体和部分带囊膜病毒及杀伤肿瘤细胞等多功能效应,在解决细菌耐药、抗病毒、调动机体的免疫功能及抗肿瘤方面有重要作用,并且一般不产生耐药性,因而其已成为当前学术界中一个引人关注的研究热点。文章就β-防御素的分子结构、生物学活性、作用机理、应用等方面做一综述。更多还原

【Abstract】 Founded extensively within creatural world in recent years,β-defensin belongs to cation poly-peptide with broad spectrum of anti-microorganism activity.The mighty function of β-defensin includes anti-bacterium,anti-epiphyte,anti-leptospira and a portion of anti-enveloped-virus as well as killing tumour cell,and play an important part in solving bacterium anti-druggery,anti-virus,mobilizing immune function and anti-tumour,with no drug-resistance commonly.So developing the research of β-defensin has become a striking hot spot in international academic circles.This article gives the β-defensin a brief description about its molecule structure,biological activity,functionary mechanism,application.更多还原