【摘要】 目的研究磷脂酶C-γ1在小鼠胚胎各组织的表达及规律。方法制备小鼠胚胎标本,进行石蜡包埋并切片,采用免疫细胞化学方法检测磷脂酶C-γ1的表达。结果各种胚胎组织中软骨、骨骼肌、心肌、肾脏集合小管、结缔组织、脑等均有不同程度的表达。结论磷脂酶C-γ1相关的信号通路对于小鼠胚胎细胞(软骨、骨骼肌、肾脏集合小管、结缔组织、脑神经元等)的发育可能具有重要的生物学意义。更多还原

【Abstract】 To investigate the expression of phospholipase C-γ1 (PLC-γ1) in mouse embryonic tissues, serial tissue sections were prepared routinely for immunocytochemistry for PLC-γ1. The results showed that PLC-γ1 was expressed in the cartilage, skeletal muscles, myocardium, the collecting tubule of the kidney, connective tissues and the brain, suggesting the important role PLC-γ1 and the related signal pathway may play in the development of mouse embryonic tissues.更多还原