【摘要】 目的:探讨实施立体定向双侧伏核微创射频毁损术10d后阿片类药物成瘾者人格特征的变化.方法:采用卡特尔16种人格因素问卷(16PF)和唐都医院神经外科自编随访问卷,对75例患者术前术后进行测评.结果:在16种人格因素中除怀疑性(P<0.05),独立性增强(P<0.05),自律性减弱(P<0.01)外,其余人格因素无显著性变化.随访调查中个别患者术后短期(3～6mo)有部分人格特征改变.结论:伏核内可能存在与人格特征相关的亚区或通路;毁损伏核内特定亚区后短期内总体人格特征变化不明显.更多还原

【Abstract】 AIM: To investigate the influences of ablating the nucleus accumbens with stereotactic surgery on 75 opioid addicts’ personalities 10 d later. METHODS: The 75 patients were evaluated before and after operation with Cattell’s Sixteen Personality Factor Test (16PF) and a self-designed questionnaire. RESULTS: Most of personality factors did not change except 3 factors: suspicion (P<0.05), independence (P<0.05) and self-control (P<0.01) which had significant differences after operation. Few personalities of few patients changed during 3 to 6 months after operation. CONCLUSION: There is an evident correlation between some subregions or neural pathways in nucleus accumbens and personalities. This operation hasn’t significant influences on the whole personalities of patients of whom the specific parts of nucleus accumbens have been damaged.更多还原