【摘要】 目的探讨常规手术(断流术、分流术)与肝移植术在治疗门脉高压症中的作用。方法对93例门脉高压症患者的外科治疗进行回顾性分析。常规手术组73例,肝移植手术组20例,术后随访24~48个月,观察再出血率和死亡率。结果肝功能ChildA或B级的患者常规手术疗效较好,ChildC级患者常规手术疗效差。肝移植手术组ChildC级患者病死率为6.6%,显著低于常规手术组ChildC级患者病死率61.5%(P<0.01)。结论有出血史但肝功能属ChildA或B级,常规手术术后能维持较好的肝脏功能和生活质量。肝功能属ChildC级,常规手术不能取得满意疗效者,肝移植术是唯一的治愈性手术。更多还原

【Abstract】 Objective To evaluate the role of conventional operation(CO, including shunting and disconnection) versus orthotopic liver transplantation operation (OLT) in treatment of portal hypertension. Methods T otally 93 cases of portal hypertension with surgery treatment were analyzed retrospectively. Rehaemorrhagia and mortality were observed between CO group (73 cases) and OLT group (20 cases). Postoperative follow-up period was 12 to 33 months. Results CO was eutherapeutic among Child A and Child B patients while reverse to Child C patients. The mortality of Child C patients underwent OLT was 6.6%(1/15), significantly lower than that of CO group(61.5%,8/13, P<0.01). Conclusion CO can maintain right postoperative liver function and life quality to Child A and B patients regardless hemorrhage history while OLT was the only curative modus to Child C patients.更多还原