【摘要】 目的比较绝经前后成年女性压力性尿失禁(SUI)的尿动力学特点,探讨绝经前后压力性尿失禁发生机制的差异。方法对116例经临床确诊的成年女性压力性尿失禁患者行腹压漏尿点压测定(ALPP)以及尿道压力图测定,按是否绝经分为未绝经组66例和绝经组50例,比较两组尿动力学特点。结果未绝经组的ALPP值、最大尿道关闭压(MUCP)较绝经组高,控制面积(CA)较绝经组大(P<0.05);而两组功能尿道长度(FUL)的差异无显著性(P>0.05)。结论绝经前后女性压力性尿失禁有不同的尿动力学特点,提示女性压力性尿失禁的发生机制在绝经前后存在一定差异。更多还原

【Abstract】 Objective To study the difference of urodynamic characteristics between premenopausal and postmenopausal stress urinary incontinence (SUI) and try to find out the different pathogenesis. Methods A retrospective study was done in 116 adult female SUI patients (66 premenopausal cases and 50 postmenopausal cases) who underwent abdominal leak point pressure (ALPP) and urethral pressure profiles (UPP). The urodynamic characteristics of each patient were analyzed and the results were compared between the two groups. Results ALPP of premenopausal group was much higher than that of postmenopausal group [(80±28) cmH 2O vs (65±28) cmH 2O, P<0.05]. The patients whose ALPP under 60 cmH 2O in premenopausal group was 14, less than 19 in postmenopausal group (21.2% vs 38%, P<0.05), whereas the patients whose ALPP above 90 cmH 2O were 20 in premenopausal group, more than 7 in postmenopausal group (30.3% vs 14%, P<0.05). While MUCP and continence area showed significant difference (P<0.05), functional urethral length showed no statistic difference between the two groups. Conclusion Premenopausal and postmenopausal SUI showed different urodynamic characteristics. It implies that the pathogenesis of SUI in the two groups was dissimilar.更多还原