【摘要】 目的总结近年来应用体外循环技术切除局部晚期肺癌侵犯心脏大血管的经验。方法回顾分析所施行的8例手术经验及结果。8例中2例肺癌侵犯降主动脉采用左心转流的方法完成了手术,其余6例均采用常规体外循环技术完成了切除手术。结果术后仅1例发生了血胸并发症,经再次开胸止血顺利恢复。术后随访1例存活6个月因脑转移死亡,另1例26个月死于全身转移。2004年所施行的6例均存活。结论扩大切除应强调良好的术前准备,严格手术适应证,病理类型仍以非小细胞肺癌为主。更多还原

【Abstract】 Objective To summarize the experience of extended resection of the heart, great vessels with cardiopulmonary bypass in the treatment of locally advanced lung cancer. Methods Lobectomy or pneumonectomy combined with extended resection of the heart, great vessels were carried out in 8 patients with locally advanced lung cancer. The operations included aorta resection and reconstruction with left heart bypass in 2 cases, extended resection of left atrium with normal cardiopulmonary bypass in 6 cases. Results Haemothorax occurred in one patient and cured. Two patients died due to brain metastasis after postoperative 6 months and multiple metastasis 26 months after operation. The others are alive. Conclusion CPB is s safe and effective tool during extended resection of locally advanced lung cancer. However, such operation is mainly fitful for non-small cell lung cancer. The indications for surgical intervention should be strictly selected and patients’ preoperative status should be adjusted to a better condition.更多还原