【摘要】 目的:初步分析不同年龄组急性心肌梗死(AMI)罪犯病变的血管内超声(IVUS)影像特点。方法:74例AMI患者按年龄分为老年(≥65岁)组29例,非老年(<65岁)组45例。应用IVUS对两组的74处病变进行分析。结果:老年组和非老年组的最小管腔横截面积、重构指数、脂池或溃疡面积、脂池或溃疡面积／斑块面积比值分别为(3．6±0．9)mm2 vs (4．2±1.1)mm2、(1．055±0．263)vs(1．188±0．245)、(2．3±0．79)mm2 vs(3．9±0．82)mm2、(21．9±4．2)vs(33．9±5．1),P均<0．05。老年组以纤维钙化斑块为主,非老年组以纤维软斑块为主,两组斑块破裂的发生率分别为51．7％vs 75．6％, P<0．05。结论:AMI的罪犯病变多因不稳定斑块发生破裂所致,但非老年组的病变相对老年组而言更加不稳定。更多还原

【Abstract】 Objective:To analysis the relationship between age and the features of the culprit lesion in acute myocardial infarction (AMI) as shown by intravascular ultrasound(IVUS) .Methods: According to age 74 selected patients who underwent IVUS were categorized as Group 1 (age≥65yrs) and Group 2 (age≤65yrs) .Coronary remodeling patterns and plaque morphology of the culprit lesion obtained by IVUS were analyzed. Results:Between the two groups, the area of minimal exterior elastic membranes, the remodeling ratio, lipid - pool or ulcer area, the ratio of lipid - pool or ulcer area to plaque area were(3.6±0.9) mm2 vs (4.2±1.1) mm2, (1.055±0.263) vs(1.188±0.245),(2.3±0.79)mm2 vs (3.9±0.82)mm2,(21.9±4.2) vs (33.9±5.1) ,51.7% vs 75.6% in Group 1 and Group 2, P < 0.05 for all. Conclusion: The rupture of unstable lesion was the crucial reason of AMI. The lesions in non - aged group are more unstable than them in aged group.更多还原