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经颅多普勒超声STI、rCBFLI与99mTc-ECD SPECT脑灌注成像半定量分析比较与应用研究

Comparisons of STI, rCBFLI by transcranial Doppler and cerebral blood perfusion imaging with 99mTc-ECD SPECT via semiquantitative analysis

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【作者】 吴钢缪蔚冰陆兵勋魏慧星林军郑依勇

【Author】 WU Gang, MIAO Wei-bing, LU Bing-xun, WEI Hui-xing, LIN Jun, ZHENG Yi-yong. Department of Neurology, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

【机构】 福建医科大学附属第一医院神经内科福建医科大学附属第一医院核医学科南方医科大学南方医院神经内科福建医科大学附属第一医院神经内科 350005 福州350005 福州510515 广州

【摘要】 目的为阐述经颅多普勒超声(TCD)的狭窄指数(STI)与局部脑血流量丧失指数(rCBFLI) 公式数理逻辑推导的合理性、实用性。方法将TCD检测的脑梗死病例中18例27条颅内动脉狭窄区的STI、rCBFLI指数与相对应区的SPECT脑血流量下降的半定量分析资料进行回顾性对比研究。结果 18例27条颅内动脉狭窄后局部脑血流量下降TCD的rCBFLI值与SPECT相对脑血流量下降值的比较呈线性模型曲线拟合,r=0.62,P<0.001,n=27;局部脑血流量下降的SPECT测量值与TCD的STI值相关曲线拟合呈复合模型曲线拟合,r=0.65,P<0.001,n=27。结论 TCD的STI 和rCBFLI计算公式可以作为评估颅内动脉狭窄程度的新指标。

【Abstract】 Objective To evaluate the rationality and utility of the formulas of STI and rCBFLI by transcranial Doppler (TCD) which were deduced by mathematical logic. Methods The indexes of TCD’s STI and rCBFLI of 27 intracranial artery stenosis areas in 18 cerebral infarction patients and the semiquantitative data of the decreased regional cerebral blood perfusion imaging in 99mTc-ECD SPECT at the corresponding areas were analyzed retrospectively. Results In 27 intracranial artery stenosis areas in the 18 cerebral infarction patients, the decreased values of TCD’s rCBFLI and the decreased SPECT values by regional cerebral blood perfusion imaging at the corresponding areas presented curve fitting of linear mode, r=0.62, P<0.001, n=27, while the decreased values of TCD’s STI and the decreased SPECT values at regional cerebral blood perfusion presented curve fitting of complex mode, r=0.65, P<0.001, n=27. Conclusion The formulas of STI and rCBFLI of TCD man be viewed as new indexes to evaluate the degree of intracalvarium arterial stenosis.

【基金】 福建省科技计划重点项目(2003Y038)
  • 【文献出处】 中华神经医学杂志 ,Chinese Journal of Neuromedicine , 编辑部邮箱 ,2006年05期
  • 【分类号】R445
  • 【被引频次】5
  • 【下载频次】148
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