【摘要】 手性药物的合成是目前全球药物开发研究的热点,而不对称氢化是手性合成中最成熟的技术.讨论了不对称氢化技术在镇痛类、抗生素类、抗菌类、抗忧郁类以及维生素类等9类手性药物合成中的实际应用.更多还原

【Abstract】 The synthesis of chiral pharmaceuticals is a hot issue of the development in pharmaceutical in the world,asymmetric hydrogenization of which is the successful technology in the chiral synthesis.The practical application of asymmetric hydrogenization in pharmaceutical,such as analgesics agents,antibiotics, antimicrobial agents,antidepressants and vitamin,are reviewed.更多还原