【摘要】 2006年度诺贝尔生理医学奖授予了美国斯坦福大学医学院病理遗传学教授安德鲁.费尔(A ndrew F ire)和马萨诸塞大学医学院分子医学教授克瑞格.梅罗(C raigM ello),表彰他们发现了“RNA-干扰,双链RNA对基因的抑制”,这是在遗传信息传递过程控制中的一个基本的机制.他们的工作不但具有重要的理论意义,而且使我们看到癌症、爱滋病、遗传病治疗的希望.文章系统地介绍了这一工作的研究背景、方法、结论,并分析了该结果在生物学中的意义.更多还原

【Abstract】 Andrew Fire of Stanford University and Craig Mello of Massachusetts University are the winners of Nobel Phisiological-Medical Prize in 2006,owing to their discovery of double stranded RNA-interfere in gene expression which is a basic mechanism of genetic information transfer.Their contribution is very significant in biological theory and in medical thrapy as well,especially in the cure of cancer,AIDS,genetic disease.The study background,methodology,conclusions and also the biological importance of their work are described in the paper.更多还原