【摘要】 机体对运动的不适应不仅可能导致铁的丢失,还可能导致铁转运障碍,铁在储铁组织(肝脏、肌肉)蓄积过多,而在耗铁组织(骨髓)又相对缺乏。这种贫富悬殊的铁分布可能是运动性贫血的发病机理之一。长期运动训练后,如果机体产生运动适应,上调转铁蛋白及其受体的表达或增强非Tf结合铁的转运,那么就会克服铁的紊乱分布,将富铁组织的铁转运到贫铁的骨髓,有利于运动性贫血发生后血红蛋白与红细胞比容的恢复,这可能是运动性贫血呈现一过性、长期运动训练后机体出现低铁而不贫血状态的原因所在。更多还原

【Abstract】 Human inadaptability to exercise induces not only the loss of iron but also the dysfunction of iron transport.The latter maybe conduces to iron excessive accumulation in the liver and muscle and iron-deficiency in the bone marrow.The iron distribution with extreme disparity can be seen as one of the reasons for exercise-induced anemia.Long-term sports training improves the disordered iron distribution by upregulating transferrin and its receptor expression,and by enhancing transferrin-free iron uptake,and by transfering iron from iron-rich tissue to bone marrow,these adaptabilities to training can conspicuously accelerate the recovery of hemoglobin and hematocrit after exercise-induced anemia.Accordingly,exercise-induced anemia is often temporary and then vanishes,long-term sports training perhaps leads to blood low iron status without anemia.更多还原