【摘要】 目的研究5种动物涎腺组织形态学及超微结构特点。方法选用成年小型猪5只,猕猴2只,新西兰白兔7只、Wistar大鼠7只和昆明小鼠7只及人类正常腮腺和颌下腺组织各一例,行腮腺和颌下腺组织学、组织化学及超微结构观察。结果5种动物的腮腺组织学表现差异不明显,均为浆液性腺体。5种动物的颌下腺组织学差异较大,人、小型猪、猕猴颌下腺均为混合性腺体,而大、小鼠和兔颌下腺为浆粘液性腺体。组化染色结果表明形态相似的腺泡细胞,其合成产物不尽相同。5种动物腮腺和颌下腺腺泡细胞在超微结构方面除分泌颗粒表现出明显的差异外,其余结构差异不明显。结论在小型猪、猕猴、兔、大鼠和小鼠5种动物的涎腺组织学及超微结构上,猕猴和小型猪与人类最接近。更多还原

【Abstract】 Objective To study the histology and ultrastructure of five species of mammalian and human salivary glands. Methods The salivary glands of five adult minipigs, 2 rhesus monkeys, 7 New Zealand rabbits, 7 Wistar rats and 7 Kun Ming mice, were studied. Normal human parotid glands and submandibular glands served as control. The histology, histochemistry and ultrastructure of these salivary glands were investigated.Results The parotid glands in five species of animals were serous glands, little difference was found among these parotid glands of five species of animals in histology. Submandibular glands of human being, minipigs and rhesus monkeys were mixed glands, while those of rats, mice and rabbits were seromucous glands. Histochemical stainings showed that the substance synthesized from acinar cells was different although these cells looked similar under light microscope. The ultrastructure of acinar cells of five species of animals’ parotid glands and submandibular glands showed little different except the secretory granules. Conclusion The salivary glands of rhesus monkeys and minipigs were histologically and ultrastructurally close to human being’s.更多还原