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人类T淋巴细胞白血病病毒流行区无偿献血人群筛查研究

Screening of Human T-lymphotropic Virus in Voluntary Blood Donors in an Endemic Area

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【作者】 陈长荣张军谢金镇张永昌王颖彬

【Author】 CHEN Chang-rong~1,ZHANG Jun~2,XIE Jin-zhen~1,ZHANG Yong-chang~1,WANG Ying-bin~2(1.Xiamen Blood Services,Xiamen 361004,China;2.The Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering,Xiamen University,Xiamen 361005,China)

【机构】 厦门市中心血站厦门大学细胞生物学与肿瘤细胞工程教育部重点实验室厦门大学细胞生物学与肿瘤细胞工程教育部重点实验室 厦门361004厦门361005厦门361004

【Abstract】 In order to evaluate the blood screening of human T-lymphotropic virus(HTLV) infection in endemic regions in China,a total of 32 767 voluntary blood donors in Xiamen during February 2004 to February 2005 were tested for anti-HTLV Ⅰ/Ⅱ using an ELISA kit.Those repeatedly positive samples were further confirmed by Western blot and PCR.Thirteen donors were positive for antiHTLV by ELISA and 7 among them were confirmed by Western blot,while one was doubtful.HTLV I env gene fragments from four confirmed samples were amplified successfully by PCR.Phylogenetic analysis showed that they were all grouped into subtype C.None of the seven confirmed donors came from Xiamen City,but from other areas of Fujian Province.Five of these 7 donors came from the coastal area of Fujian Province,while the other two came from inland area.

  • 【文献出处】 病毒学报 ,Chinese Journal of Virology , 编辑部邮箱 ,2006年01期
  • 【分类号】R446.6
  • 【被引频次】2
  • 【下载频次】166
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