【摘要】 目的探讨50g葡萄糖筛查试验(50gglucosechallengetest,50gGCT)异常孕妇的进一步诊断策略。方法回顾性分析2004年1月~2005年12月行50gGCT1055例孕妇的资料及50gGCT阳性孕妇口服葡萄糖耐量试验(OGTT)结果。结果50gGCT的结果越高孕妇诊断为妊娠期糖尿病(GDM)或妊娠期糖耐量减低(GIGT)的比例越高,当50gGCT≥10.6mmol/L时,异常检出率明显增加(P<0.005),且诊断为GDM的平均空腹血糖仅为5.2mmol/L;50gGCT≥12.8mmol/L时,诊为GDM的孕妇为100%。结论葡萄糖筛查试验对诊断GDM十分必要,但不能用于确诊;孕期空腹血糖敏感度低,不能使用国外的诊断标准;当50gGCT≥12.8mmol/L时可不行OGTT试验,直接诊断为GDM。更多还原

【Abstract】 Objective:To investigate the further diagnosis for the pregnant women with abnormal 50 g glucose challenge test(50 g GCT).Methods:The data of 1 055 pregnant women in outpatient from January 2004 to December 2005 undergoing 50 g GCT,were analyzed retrospectively.Oral glucose tolerance test(OGTT) was analyzed for pregnant women with positive glucose challenge test.Results:The higher the positive ratio of 50g GCT was,the higher proportion of gestational diabetes mellitus(GDM) or gestational impaired glucose tolerance(GIGT) was.If the result of 50 g GCT ≥10.6 mmol/L,the ratio of diagnosis was significantly higher(P< 0.005 ),and average limosis blood sugar for diagnosing GDM was only 5.2 mmol/L.If it ≥12.8 mmol/L,100% pregnant women was diagnosed with GDM.Conclusions:GCT is essential for GDM except for ascertaining diagnosis.Because the sensitivity of limosis blood sugar of pregnant women is less,the foreign criteria can not be used.When the result of 50 g GCT≥12.8 mmol/L,GDM can be diagnosed without OGTT test.更多还原