【摘要】 目的探讨影响食管癌放疗过程中靶中心移位的相关因素。方法对299例食管癌患者于肿瘤剂量达40Gy时在模拟定位机下用游标卡尺测量出新的照射野中心点(新靶中心)与原照射野中心点(原靶中心)之间在X轴(左右方向)和Y轴(上下方向)上的偏移距离。结果299例患者靶中心左右移位发生率为80.6%,上下移位发生率为66.9%。移位与病变部位、病变长度、软组织肿块影、X线大体类型均有明显关系(P<0.01~P<0.005),不同病理类型与靶中心移位均无明显关系(P>0.05)。结论食管癌的病变部位、病变长度、X线大体类型、软组织肿块影可能是影响靶中心偏移的相关因素。更多还原

【Abstract】 Objective:To explore the related factors of target center bias in the course of radiotherapy for esophageal carcinoma.Methods:The target center bias(between the original target center and the new target center) of 299 cases with esophageal carcinoma was measured with the sliding caliper on X-axis and Y-axis under the simulator when the dose reached 40 gery.Results:The target center bias was found in 241 of the 299 cases on X-axis(80.6%),and 200 of the 299 cases on Y-axis(66.9%).Target center bias was obviously related to the tumor location(P<0.01),tumor length(P<0.01),soft tissues umbra(P<0.01) and the typing on X-ray film(P<0.01-P<0.005),pathology types had no obvious relation with the target center bias (P>0.05).Conclusions:The tumor location,tumor length,soft tissues umbra and typing on X-ray film may be the contribution factors for the target center bias in radiotherapy for patients with esophageal carcinoma.更多还原