【摘要】 目的　初步探讨无创性多层CT冠状动脉造影 (MSCTCA)的临床应用价值及局限性。方法　收集进行多层CT冠状动脉造影患者 2 0例 (临床疑诊为冠心病者 15例 ,冠状动脉血管成形术并置入支架者 5例 )。以管腔直径减少≥5 0 %作为判定狭窄的标准 ,对各冠状动脉主要分支进行节段分析 ,并与传统冠状动脉造影结果进行对比。结果　 84.4%的冠脉节段图像质量可以进一步评价。MSCTCA检出冠状动脉病变的敏感度为 75 % ( 6/ 8) ,特异度为 94.9% ( 13 1/ 13 8)。对于支架节段 ,MSCTCA可准确显示支架位置、形态及远端血流情况 ,可排除支架闭塞及高度狭窄。结论　多层CT冠状动脉造影可显示较长节段的冠状动脉 ,较为准确地认定冠状动脉病变 ,有潜力成为无创性诊断冠状动脉疾病的有力工具。更多还原

【Abstract】 Objective To investigate the potential clinical values and limitations of non invasive coronary angiography with multi slice computed tomography. Methods Twenty patients were studied by both MSCTCA and conventional coronary angiography (including 15 cases who were suspected clinically coronary heart disease, 5 cases who had undergone PTCA). The segements of main coronary arteries in MSCTCA were compared with conventional angiography, and ≥50% reduction of vessel diameter was defined as significant disease. Results 84.4% of the coronary segments were accessible. The sensitivity of detection significant stenosis with MSCTCA was 75%(6/8), the specificity was 94.9% (131/138). In the segments with stents, MSCTCA can display the position, shape and distal blood flow, so the occlusion and serious stenosis of stents can be excluded. Conclusion MSCTCA has the potential to develop into a reliable technique to diagnose coronary artery disease.更多还原