【摘要】 目的　评价三维脂肪抑制快速毁损梯度回波序列 (3DFS FSPGR)对髌股关节软骨病变的诊断能力。方法　 5例尸体膝关节 ,对 1例髌股关节用不同参数的 3DFS FSPGR序列轴位扫描 ,找出软骨 /液体和软骨 /骨髓对比噪声比最佳的参数。用该参数的 3DFS FSPGR序列扫描另外 4例髌股关节。所有髌股关节均另外作 3DFS SPGR序列扫描。用双盲法对髌股关节的大体标本和MRI进行软骨病变的评价 ,计算每种序列诊断髌股关节软骨病变的敏感性、特异性和总符合率。结果　 3DFS FSPGR序列扫描时间为 1分 3 2秒 ,其诊断髌股关节软骨病变的敏感性、特异性和总符合率为 92 %、71%和85 % ;3DFS SPGR序列扫描时间为 4分 5 5秒 ,其诊断髌股关节软骨病变的敏感性、特异性和总符合率为 92 %、86%和90 %。结论　 3DFS FSPGR序列对软骨病变的诊断能力与 3DFS SPGR相当 ,但扫描时间仅约为其 1/ 3。更多还原

【Abstract】 Objective To evaluate the role of 3D FS FSPGR sequence in the assessment of abnormalities of patellofemoral joint cartilage. Methods Five cadaveric knees were injected 40ml of saline prior to imaging. Optimization of the 3D FS FSPGR sequence was achieved by axial imaging the first cadaveric knee. The other 4 cadaveric knees were imaged by the sequence which had the highest contrast to noise ratio for cartilage/fluid and cartilage/bone marrow. Three dimensional fat suppressed spoiled gradient recalled echo (3D FS SPGR) sequence also was used in imaging of all 5 cavaveric knees. The macroscopic sections and MR images of each region were evaluated by two orthopaetic doctors and two radiologists respectively. The sensitivity,specificity and accuracy of each sequence were calculated. Results The acquisition time of 3D FS FSPGR sequence was 1 minute 32 seconds,the sensitivity,specificity and accuracy of which were 92%,71%,85%. The acquisition time of 3D FS SPGR sequence was 4 minutes 55 seconds,the sensitivity,specificity and accuracy of which were 92%,86%,90%. Conclusion 3D FS FSPGR sequence had similar role to 3D FS SPGR sequence in the assessment of abnormalities of patellofemoral joint cartilage and took about one third acquisition time that 3D FS SPGR sequence did.更多还原