节点文献
一阶导数光谱法测定复方炉甘石氯霉素洗剂中氯霉素的含量
Determination of Calamine Chloramphenicol Lotion Compound by First Order Derivative Spectrophotometry
【摘要】 目的:建立复方炉甘石氯霉素洗剂中氯霉素的含量测定方法。方法。采用一阶导数分光光度法不经分离直接测定氯霉素的含量,检测波长为299nm。结果:线性范围为24~40μg·ml-1,r=0.9997,平均回收率98.6%,RSD为0.9%。结论:本方法可消除其它组分的干扰,简便易行,适合医院制剂的质量控制。
【Abstract】 Objectives: To establish a method to determine the content of chloramphenicol in calamine chloramphenical lotion compound. Method: The first order derivative spectrophotometry was used to determine the chloramphenicol without separation. The detecting wavelength was at 299 nm. Result; The method was linear within rangeof 24-40 ug ml-1 (r = 0.999 7). The average recovery was 98.6% with RSD 0.9%. Conclusion: The interference of the other components can be excluded by this method, which is simple, rapid and accurate. It is suitable for the quality control of hospital preparation.
【Key words】 Spectrophotometry, first order derivative; Chloramphenicol; Calamine;
- 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,2002年08期
- 【分类号】R927.2
- 【被引频次】1
- 【下载频次】27