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病毒感染与小儿短暂性滑膜炎关系的研究

RELATIONSHIP BETWEEN JUVENILE TRANSIENT SYNOVITIS AND VIRAL INFECTION

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【作者】 付学东沈先涛刘江勤余立平

【Author】 Fu Xuedong,Shen Xiantao, Liu Jiangqin, et al. Zhongnan Hospital, Wuhan University, Wuhan 430071

【机构】 武汉大学中南医院儿科武汉市儿童医院骨科武汉大学中南医院儿科 430071430016430071430071

【摘要】 探讨小儿短暂性滑膜炎与病毒感染 ,特别是柯萨奇B组病毒 (CVB)感染的关系。方法 :采用酶联免疫吸附试验 (ELISA)对 16 2例小儿髋关节短暂性滑膜炎患儿静脉血和其中的 2 1例关节腔液进行病毒IgM抗体检测 ,柯萨奇病毒B组 (CVB)阳性者进行血清学分型及病毒分离。结果 :在 16 2例静脉血样本中病毒IgM阳性 6 2例 ,占总检数的 38.2 7% ,CVB -IgM2 6例占 16 .0 5 % ,AdV -IgM 19例占 11.73% ,CMV -IgM 10例占 6 .17% ,RSV -IgM 4例占 2 .4 7% ;在关节腔液中检出 9例CVB阳性 ,血清学分型 8例为CVB3,1例为CVB4 ,并分离出 1例CVB3。结论 :CVB和腺病毒 (AdV)是小儿髋关节短暂性滑膜炎感染的主要病毒 ,而且以CVB3为主。

【Abstract】 Objective:To determine the relationship between juvenile transient synovitis of the hip and viral infection. Methods:EV-IgM antibody was detected with ELISA in blood and arthrocentesis. At the same time, sample with coxsackievirus B(CVB) IgM positive was tested by serptype. Results:IgM antibody was detected in 38.27% in blood of the patients and in 76.19% in arthrocentesis. CVB-IgM was found positive in 16.05% of blood and in 42.86% of arthrocentesis.AdV-IgM was in 11.73% and in 23.81%, respectively. Most of the CVB-IgM positive individuals were infected with CVB3.Conclusions:The results of this study suggest that there may be a significant correlation between juvenile transient synovitis and CVB and AdV, especially CVB3.

  • 【文献出处】 中国现代医学杂志 ,China Journal of Modern Medicine , 编辑部邮箱 ,2002年15期
  • 【分类号】R726.8
  • 【被引频次】6
  • 【下载频次】43
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