【摘要】 目的 观察电针“足三里”对自发性高血压大鼠(SHR)血压及心率、血清一氧化氮(NO)、血浆内皮素(ET)含量的影响,探讨电针降压的可能机制。方法 选择自发性高血压大鼠16只,分为电针组、空白组,电针组电针双侧“足三里”,3个疗程后测量颈动脉插管的平均动脉压及心率、血清一氧化氮、血浆内皮素含量的变化。结果 ①电针可降低SHR血压,颈动脉插管测得电针组血压 (161±14.86)mmHg,空白组(190±21.21)mmHg,电针组血压较空白组血压显著下降(P<0.01);②电针组血清NO为(37.67±10.4)μmol/L,明显高于空白组的(25.72±4.53)μmol/L(P<0.05);③电针组血浆ET为(154.39±51.69)pg/ml,空白组(145.517±31.74)pg/ml,两组SHR的血浆ET含量无明显差异。④两组 SHR大鼠心率分别为(360±32.51)次/min和(365 ±23.3)次/min,两组SHR大鼠心率无明显性差异。结论 电针可降低SHR血压及调整外周NO含量,但对心率、血浆ET含量无明显影响。而SHR血压与外周NO含量存在一定的相关性。更多还原

【Abstract】 Obwhve To obom the effeCt ofelectlxxltiupunt—。。。 bled pressure (B), hewt mte,。ncentra。serum nitric oxide (N) and plasm endothlin(Ef) Of spontaneous hypertension rats(SHR). Methch S31ix!T 16 StiRs, dVltlts 11C’111’ito OltX:Mup1CILllts gnup, Ic DlllK COllW grUup· I:’lt3t:CCpCICL IC Xiljbi1Jtu OI LWO SlOts UIL’M LILMupMItill:e gi’Oup.川卜r凸叵咒hant comes,measllle b mean allery pmesllre…common caotid artery cannadasand concentrationSerUm m d pl。 gy.吼隅。e加ir cbos. Redis皿er ti。 treflllllt,nt c。s, l. L edPjS皿 can ed Muced. TBPsobtal饲…。ncatntldaxteryc。"las。: 16ltl4.86mnMg,el。mia。p。pgroup; loptZI.21wi,比讪。Mmp. h朋1如tit)aCupunttlxe pop5as*UCed st咖candy comPared…1“t J6falll’ cont饲 group(2< 0测.:账 co。咖讪J。 md如恤删u卿ct。 puP is 37.O* 10.4呷风, s…can… hi扣肠佃 jblank COed卵晒.72士岑.53twL)(P<0.历).3.(kJllflent18tlonofplasm皿ofelectroaCupinct。grollpis**t51.69pgilnl, blaJcond gIDup比历 t 31.74 pgiwh thare is no siedCan (lllletxtllc Isel:wren two groups( P> 0.05) 4皿 healt rae of小tIDape mp is 3fol 32,sl tllll｛3s/。n,blank conbol mp 365 f 23,3 ti。s/nun,th,re Is no s…c。t (llJIf。e lreTwestWO gnupe( P> 00汕h恤啊…腑 can rerlljce the bled mpe of SHR and adwt conCenration ofperiped m. There is删例ation htween UM ptessllle and concentrationl penplle觎 Nltnc (,xl. There Is no ohous咖t j小更多还原