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常规与小剂量胺碘酮转复房颤的疗效及副作用的对比研究

Comparative study of the effect and side-effects of common and small dose amiodarone on cardioversion for atrial fibrillation

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【作者】 梅霞李法琦郑向清王骄

【Author】 MEI Xia(Department of Cardiology , Chongqing Zhongsan Hospital)

【机构】 重庆市中山医院心内科重庆医科大学临床学院内科重庆市中山医院心内科 重庆400013重庆400016重庆400013重庆400013

【摘要】 目的:观察常规与小剂量胺碘酮对房颤转复的疗效及副作用。方法:设治疗组(小剂量胺碘酮,每日~)0.10.2g与对照组(常规剂量胺碘酮,每日~)治疗例房颤患者,观察用药后个月房颤发作控制率及药物副作用。0.30.4g1226结果:治疗组与对照组比较,房颤控制率相近(P)、副作用小(>0.05P)。<0.01结论:小剂量胺碘酮治疗房颤有效且副作用小。

【Abstract】 Objective: To observe the effect and side-effects of common and small dose amiodarone on cardioversion for atrial fibrillation. Methods: 122 patients with atrial fibrillation were randomly divided into treatment group(small dose amiodarone, 0.1~0.2g/ per day) and control group(common dose amiodarone, 0.3~0.4g/ per day). After 6 months, the effect and side-effects of common and small dose amiodarone on cardioversion for atrial fibrillation were compared. Results: The cardioversion and control rates of atrial fibrillation were no significant difference between 2 groups (P>0.05), but the incidence of side-effects of amiodarone in treatment group was lower than that in control group (P<0.01). Conclusion: small dose amiodarone is effective for treatment of atrial fibrillation and the incidence of side-effects of small dose amiodarone is lower than that of common dose amiodarone.

【关键词】 胺碘酮房颤治疗副作用
【Key words】 AmiodaroneAtrialfibrilatiomTherapySide-effect
  • 【文献出处】 重庆医科大学学报 ,Acta Universitatis Scientiae Medicinae , 编辑部邮箱 ,2002年03期
  • 【分类号】R541.7
  • 【被引频次】2
  • 【下载频次】49
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