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转基因产品致敏性评估的规范化

Standardization of Allergenicity Assessment of Transgenic Products

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【作者】 倪挺; 胡鸢雷; 林忠平; 李宏; 张宏誉; 彭于发; 董志峰;

【Author】 NI Ting 1, HU Yuan lei 1, LIN Zhong ping 1, LI Hong 2, ZHANG Hong yu 2, PENG Yu fa 3, DONG Zhi feng 4 ( 1The National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing 100871; 2Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730; 3Institute of Plant Protection, Chinese Acadmy of Agricultural Sciences, Beijing 100094; 4Development Center of Bio engineering, the Ministry of Science and Technology, Beijing 100081)

【机构】 北京大学蛋白质工程及植物基因工程国家重点实验室; 中国协和医科大学北京协和医院变态反应科; 中国农业科学院植物保护研究所; 中国国家科技部生物工程开发中心生物资源与生物安全处 北京100871; 北京100871; 北京100730; 北京100094; 北京100081;

【摘要】 在转基因产品商业化之前需要对其安全性进行全面评估 ,其中包括对潜在致敏性的评价。介绍了多个国际组织对致敏性的评估程序 ,并对致敏性测试的某些环节进行了论述。随着中国加入WTO以及在国际贸易中转基因产品数量和品种的增加 ,我国对转基因产品食用安全性中致敏性的评估程序及评估技术与国际接轨日益重要。笔者建议尽早建立一套适合中国国情的科学而又全面的转基因产品潜在致敏性评估体系

【Abstract】 Before any GM (genetically modified) food entering market, it has to be comprehensively evaluated for safety in nutrition, toxicology, allergenicity, and other aspects of food science. This article gives a brief review on allergenicity assessment approaches proposed by several international organizations. A variety of tests and questions should be considered to determine whether the GM product has any increased risk of allergenicity. Along with economic globalization, it becomes more and more important for safety assessment of GMO (genetically modified organism) allergenicity be conformed with international standards. It is in urgent need to establish a comprehensive and scientific assessment system on allergenic potential that could reflect current technical conditions in China.

【关键词】 GMO; 致敏性评估; 转基因;
【Key words】 GMO; Allergenicity assessment; Transgene;
【基金】 国家“973”课题资助项目 (2 0 0 1CB10 90 0 )
  • 【文献出处】 中国农业科学 ,Scientia Agricultura Sinica , 编辑部邮箱 ,2002年10期
  • 【分类号】Q788
  • 【被引频次】11
  • 【下载频次】150
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