【摘要】 对黄药子 (DioscoreabulbiferaL .)的乙醇浸提物进行了柱层析分离 ,并以MetAP2为靶标对各分离组分进行了活性测定 ,在黄药子中首次找到了对MetAP2具有强活性的物质 ,并对其进行了质谱分析 ,鉴定出其结构为 1 - (3 -丙氨基 ) - 2 -甲基哌啶更多还原

【Abstract】 The ethanol extraction of Dioscorea bulbifera L. was separated by column separation method, and the activity of the fractions was determined by using Methionine aminopeptidase (type 2) as the target. It was the first reported that the ingredient with high anti-tumor activity was 1-(3-aminopropyl)-pipecoline based on wass spectrometry.更多还原