【摘要】 采用参数相关分析的发酵过程优化理论对红霉素发酵过程进行研究 ,发现红霉素产生菌发酵初期的菌体生长状态对整个发酵过程及最后的生产水平都会产生较大的影响 ,即所谓红霉素发酵次级代谢的混沌现象 ,通过对红霉素早期的有效控制 ,取得了显著的效果。更多还原

【Abstract】 Multi parameter corelation analysis technology was applied to the production of erythromycin. It was found that the growth state in the initial phase would affect the whole process of the erythromycin fermentation as well as its final potency, that is the phenomenon of chaos during the secondary metabolism of the erythromycin fermentation. The productivity was greatly improved through effective control on the early phase of the process.更多还原