【摘要】 目的 观察阵发性房颤患者血浆中D -二聚体纤维蛋白原及纤维蛋白降解产物水平变化 ,并探讨其临床意义。 方法 阵发性房颤组患者22例 ,对照组14例 ,均抽取肘静脉血检测血浆D二聚体、纤维蛋白原、纤维蛋白降解产物的水平。 结果 阵发性房颤组患者血浆D二聚体水平 (251.4±62.3)ng/ml明显高于对照组(205.1±49.2)ng/ml(t=2.349,P<0.05) ;而纤维蛋白原、纤维蛋白降解产物水平 (268.1±50.2)mg/dl、(3.01±1.12)mg/L与对照组 (242.7±42.8)mg/L、(2.55±1.24)mg/L相比无明显变化 (t=1.813、1.153 ,P>0.05)。 结论提示阵发性房颤患者可能存在血栓前状态 ,必要时应给予抗凝治疗。更多还原

【Abstract】 Objectives To investigate changes of plasma fibrin D-Dimer(DD),fibrinogen(Fg) and fibrin degradation products(FDP) in patients with paroxysmal atrial fibrillation(PAF) and to study their clinical significance.Methods Levels of plamsa DD,Fg and FDP were measured in 22 patients with PAF and 14 patients with sinus rhythm.Results Plasma DD level in PAF group was significant higher than that in sinus rhythm group(P<0.05),but there were no significant differences(P>0.05) between two groups in Fg or FDP.Conclusions There might be a prothrombotic state(PTS) in patients with PAF,and anticoagulant therapy may be indicated in PTS.更多还原