【摘要】 目的　探讨利用声学密度 (AD)定量技术早期评价急性心肌梗死 (AMI)患者行直接经皮冠状动脉腔内成形术 (PTCA)的手术疗效。方法　将 4 0例AMI患者分为两组 :18例病人行直接PTCA治疗 (A组 ) ,2 2例病人用药物治疗 (B组 ) ,比较两组病人在入院第 7天时常规超声心动图检查和用AD技术检测的结果。结果　两组病人常规超声心动图各项检查结果比较差别无显著性 (P >0 0 5 )。AD定量检测结果 :A组的背向散射积分周期变化幅度 (CVIB) (4 2± 1 3)dB明显高于B组 (2 5± 2 4 )dB(P <0 0 1) ;A组校正的周期变化延迟时间 (N Delay) 1 0 9± 0 0 8明显低于B组 1 31± 0 16 (P <0 0 1) ;两组间背向散射积分 (IBS)差异无显著性 (P >0 0 5 )。结论　AD技术能够早期反映AMI再灌注心肌的组织学特征 ,为早期评价介入治疗效果、预测心功能改善情况、判定心肌活性提供了一种新的技术手段。更多还原

【Abstract】 Objective To evaluate the effect of direct percutaneous transluminal coronary angioplasty (PTCA) in early stage in acute myocardial infarction (AMI) by acoustic densitometry (AD) technique Methods 40 patients with AMI were divided into 2 groups: 18 patients with direct PTCA (group A),22 patients with medical treatment (group B) The results of 2 D echocardiography and AD examination were studied on both groups at 7 days after admission Results There was no statistical difference in routine echocardiography between the two groups The results of AD examination showed: cyclic variation of integrated backscatter (CVIB) in group A was (4 2±1 3)dB, it was significantly higher than that in group B (2 5±2 4)dB ( P <0 01), calibration of delayed time of cyclic variation of integrated backscatter (N Delay) of group A was 1 09±0 08, it was significantly shorter than that of group B (1 31±0 16, P <0 01); no significant difference was seen in integrated backscatter (IBS) between the two groups ( P >0 05) Conclusion AD technology can reflect the changes of tissue characteristics in reperfused myocardia early It is a new technology for evaluating the effect of interventional therapy, predicting the improvement of cardiac function, and assessing the myocardia viability更多还原