【摘要】 目的　研究我国医用诊断X射线工作者中高血压病发病的危险因素 ,探讨长期职业受照与高血压发病之间的关系。方法　采用整群随机抽样的方法 ,在全国范围内选取 2 88对 1∶2配比的医用诊断X射线工作者高血压患者及相应对照 ,问卷调查各种可能的危险因素 ,归一化工作量法估算累积受照剂量 ,SAS软件COX比例风险模型进行单因素及多因素条件Logistic回归分析。结果　超重 (OR =3 0 87,P =0 0 0 1)、高血压家族史 (OR =3 14 0 ,P =0 0 0 1)、担心从事放射工作有害健康 (OR =1 798,P =0 0 10 )是我国X射线工作者高血压 3个主要危险因素 ;将性别、参加工作年代分层后 ,男性、早期参加放射工作者中较大剂量受照同高血压呈正相关 (OR =5 6 72 ,P =0 0 2 2 )。结论家族史、超重是X射线工作者高血压主要危险因素 ,职业紧张在X射线工作者高血压中发挥一定的作用 ,较大剂量受照可能与高血压有关更多还原

【Abstract】 Objective\ To investigate the risk factors of essential hypertension in medical diagnostic X\|ray workers in China,especially for the relationship between essential hypertension and occupational irradiation. Methods\ A 1∶2 matched case\|control study was carried out.The study subjects consisted of 288 pairs of matched cases and controls coming from different hospitals in China.Information about occupational and non\|occupational risk factors were obtained through questionnaire.Individual doses were estimated by normalized workload method.Conditional Logistic regression method was applied to data analysis with SAS6\^12 software. Results Variables such as overweight (OR=3 087, P =0 001),family history of hypertension (OR=3 140, P =0 001),worring about X\|ray work as a health\|damaging occupation (OR=1 798, P =0 010) were three main risk factors in the ungrouped data.Dividing the study subjects into different subgroups according to sex and calendar period of entry,the highest level of accumulated dose (>300 mGy) as a risk factor had statistically reached significant level in the male X\|ray workers of the earlier period of entry (OR=5 672, P =0 022). Conclusion For medical diagnostic X\|ray workers,overweight,family history of hypertension and occupational stress are the main risk factors of essential hypertension.For those accumulated doses over 300 mGy,indicating ionizing radiation may be a potential risk factor.As there is no reasonable biological mechanism to explain these findings,further studies are needed.更多还原